Page last updated: October 2026

ESMO 2026

ESMO-2026-Capdevilla-Presentation
Subgroup analysis of the ongoing Phase Ib DAREON®-7 study: Outcomes with first-line obrixtamig plus standard of care in neuroendocrine carcinomas by DLL3 expression status
Author(s): Capdevila et al.
NEC/epNEC DLL3/CD3 TcE Presentation
ESMO-2026-Vandamme-Poster
DAREON®-NEC-1: Phase III trial of first-line (1L) obrixtamig plus carboplatin and etoposide (SoC) vs SoC in patients with delta-like ligand 3 (DLL3)-positive extrapulmonary neuroendocrine carcinoma (epNEC)
Author(s): Vandamme et al.
NEC/epNEC DLL3/CD3 TcE Poster
ESMO-2026-Wermke-Poster
DAREON®-9: A Phase Ib open-label dose escalation/confirmation study of obrixtamig (BI 764532) plus topotecan in patients with extensive-stage small cell lung cancer (ES-SCLC) ‒ topotecan use analysis
Author(s): Wermke et al.
SCLC DLL3/CD3 TcE Poster
ESMO-2026-Harrington-Poster
Updated Phase Ia results with systemic STING agonist BI 1703880 plus ezabenlimab in patients with advanced solid tumors
Author(s): Harrington et al.
Solid tumors STING agonist, PD-1 inhibitor Poster

WCLC 2026

WCLC-2026-Leal-Poster
DAREON®-Lung-1: Phase III trial of first-line obrixtamig plus standard of care (atezolizumab, carboplatin, and etoposide) versus standard of care in ES-SCLC
Author(s): Leal et al.
SCLC DLL3/CD3 TcE Poster

ASCO 2026

ASCO-2026-Gambardella-Poster
Analysis of delta-like ligand 3 (DLL3) expression levels and characteristics of patients with advanced extrapulmonary neuroendocrine carcinomas (epNECs) from an ongoing Phase I trial
Author(s): Gambardella et al.
NEC/epNEC DLL3/CD3 TcE Poster
ASCO-2026-Peters-Poster
DAREON®-8: updated efficacy and safety from a Phase I dose-escalation/expansion trial of first-line obrixtamig plus chemotherapy and atezolizumab in extensive-stage small cell lung carcinoma
Author(s): Peters et al.
SCLC DLL3/CD3 TcE Poster

ELCC 2026

ELCC-2026-Mazieres-Presentation
A Phase I dose escalation trial of obrixtamig + ezabenlimab in patients with small cell lung cancer (SCLC) or other neuroendocrine carcinomas (NECs) expressing DLL3
Author(s): Mazières et al.
SCLC + NEC/epNEC DLL3/CD3 TcE Presentation

ENETS 2026

ENETS-2026-Capdevila-Presentation
DAREON®-7: Phase I open-label dose-escalation/expansion study of first-line obrixtamig (BI 764532) plus platinum-doublet chemotherapy in patients with DLL3-positive neuroendocrine carcinomas
Author(s): Capdevila et al.
NEC/epNEC + LCNEC-L DLL3/CD3 TcE Presentation

ASCO GU 2026

ASCO-GU-2026-Navarro-Gorro-Poster
Efficacy and safety of the DLL3/CD3 T-cell engager obrixtamig in patients with extrapulmonary neuroendocrine carcinomas of genitourinary origin with high or low DLL3 expression: results from an ongoing Phase I trial
Author(s): Navarro-Gorro et al.
NEC/epNEC DLL3/CD3 TcE Poster

NANETS 2025

NANETS-2025-Chauhan-Poster
DAREON®-7: Phase I open-label dose-escalation/-expansion study of first-line obrixtamig (BI 764532) plus platinum-doublet chemotherapy in patients with DLL3-positive neuroendocrine carcinomas
Author(s): Chauhan et al.
NEC/epNEC, LCNEC-L DLL3/CD3 TcE Poster
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Beamion™ LUNG-3 

Learn about the Beamion™ LUNG-3 trial.

Obrixtamig (DLL3/CD3)

Learn about our Phase III DLL3/CD3 T-cell engager (obrixtamig) trials.

Vault id: SC-CRP-16532